Ser1333 phosphorylation indicates ROCKI activation
نویسندگان
چکیده
منابع مشابه
Phosphorylation primes vinculin for activation.
Vinculin phosphorylation has been implicated as a potential mechanism for focal adhesion growth and maturation. Four vinculin residues-Y100, S1033, S1045, and Y1065-are phosphorylated by kinases during focal adhesion maturation. In this study, phosphorylation at each of these residues is simulated using molecular dynamics models. The simulations demonstrate that once each phosphorylated vinculi...
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ژورنال
عنوان ژورنال: Journal of Biomedical Science
سال: 2013
ISSN: 1423-0127
DOI: 10.1186/1423-0127-20-83